Webthe nucleophile is the aromatic ring of salicylamide. The electrophile is I+ Why is an oxidation agent needed in electrophilic aromatic substitution in order to generate the electrophile for iodination (as compared to chlorinations and … WebMar 5, 2024 · I attributed this to a few reasons, possibly due to hydrogen bonding or due to the dissociation of the O − H bond, which is driven to the right hand side of the equilibrium by the presence of the EWG amide group. 1672.98 c m − 1 is due to the C = O stretch of the amide. 1628.09 and 1589.49 c m − 1 are due to C = C aromatic stretches.
Iodination of Salicylamide : r/chemhelp - Reddit
WebIodination of Salicylamide Could someone explain the iodization of salicylamide to me? I have this reaction that is Salicylamide + NaI with NaOCl in ethanol -> iodosalicylamide. I understand where the I+ needs to be, but I don’t know how to aquire the I+ from this. WebSalicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies. fake twin ultrasound
organic chemistry - Mechanisms involved in iodination of salicylamide …
WebIntroduction In the Iodination of Salicylamide, the objective to obtain was to successfully perform an electrophilic aromatic substitution. Electrophilic aromatic substitution is one of the most important reactions possible on an aromatic ring, and one of the most common. WebUnformatted text preview: Iodination of Salicylamide Objective: You will be performing a Green Chemistry alternative to the traditional electrophilic aromatic iodination, isolating the crude product, recrystallize it and analyze the product by FT-‐IR, 1H NMR and melting point.Reactions: + NaI NaOCl I OH O OH O I NH 2 NH 2 I Salicylamide Background • … WebOct 1, 2008 · Abstract. We developed an alternative electrophilic aromatic substitution reaction for the organic chemistry teaching laboratory. The experiment is an electrophilic … fake ultrasound free