TīmeklisLAMP1:LAMP2. 溶酶体相关膜蛋白1和2(LAMP1: LAMP2)是溶酶体膜的组成部分,因此构成了极佳的溶酶体标志物,以此来作为溶酶体的maker再合适不过。 更多 … Tīmeklis2024. gada 14. maijs · Immunoblotting revealed a dose-dependent increase of LAMP2 (Fig. 3a) and LAMP1 (Fig. 3b) in cytosolic fractions, while no significant alteration was observed in the remaining lysosomal...
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LAMP2 has been specifically implicated in tumor cell metastasis. Both LAMP1 and LAMP2 have been found expressed on the surface of cancerous tumors, specifically in cells of highly metastatic cancer such as colon cancer and melanoma. They are rarely found on the plasma membranes of normal cells, and are found more on highly metastatic tumors than on poorly metastatic ones. LAMP2, along with LAMP1, interact with E-selectin and galectins to mediate the adhesion of so… Tīmeklis2013. gada 6. jūn. · In humans, mutations in LAMP2 cause Danon disease, believed to arise from aberrant autophagy. 20 LAMP2-deficient mice also accumulate autophagic vacuoles in several tissues. 21 LAMP1-deficient mice have an almost normal phenotype but have elevated levels of LAMP2, suggesting that LAMP2 can compensate for the … 餅 チョコ大福
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TīmeklisLysosome-associated membrane protein 1 and 2 (LAMP1 and LAMP2) are two abundant lysosomal membrane proteins (1,2). Both are transmembrane proteins and … TīmeklisLAMP2. LAMP2 mutations produce the multisystemic disorder, Danon disease, in which neurologic, skeletal muscle, and hepatic involvement occur with cardiomyopathy. … Tīmeklis2024. gada 1. apr. · Lysosomal-associated membrane protein 1 (LAMP1) mainly localizes to lysosomes and late endosomes. We herein investigated the intracellular localization of lysosomal membrane proteins in five... 餅つき 28日