2024 Human metastatic cancer database

Human metastatic cancer database

Author: dwlm

August undefined, 2024

Web8 Jun 2024 · Rucaparib is a PARP inhibitor approved in the United States for the treatment of patients with deleterious BRCA1 or BRCA2 (BRCA) mutation-associated metastatic castration-resistant prostate cancer (mCRPC) who have been treated with androgen receptor-directed therapy and a taxane-based chemotherapy [].The accelerated approval … Web20 Sep 2024 · Introduction: Lung metastasis is usually associated with poor outcomes in cancer patients. This study was performed to characterize and analyze the population of patients with de novo (synchronous) lung metastases using the Surveillance, Epidemiology and End Results (SEER) database.Materials and Methods: Baseline characteristics of …

HCMDB: the human cancer metastasis database. - Europe PMC

Web9 Dec 2024 · Ideally, it would be possible to construct a map of organ-specific metastatic potential of hundreds of human cancer cell lines using xenograft models, so that the … Web17 Dec 2024 · A single cell atlas of the malignant and adjacent non-malignant human liver is presented. Recurring stromal cell gene expression signatures are found in liver metastases and cholangiocarcinomas. Tumor and stromal cells communicate through a conserved ligand-receptor interaction network. gold and oxygen

Commitment of Scaffold Proteins in the Onco-Biology of Human …

WebHCMDB: the human cancer metastasis database Guantao Zheng1,2, Yijie Ma1, Yang Zou1,AnYin2, Wushuang Li1 and Dong Dong1,* 1Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai 200241, China and 2Shanghai Majorbio Bio-pharm Biotechnology … Web10 Dec 2024 · Metastatic cancer patient data. Data on 500 cancer patients with metastatic disease from 30 primary sites and biopsied from 22 organs was obtained from MET500 … WebAngiotropism is a prognostic factor predicting risk for metastasis in human melanoma, and a marker of EVMM in several experimental models. Importantly, analogies of EVMM and pericytic mimicry include neural crest cell migration, vasculogenesis and angiogenesis, and recent studies have suggested that the interaction between melanoma cells and ... gold and oxygen reaction

IJMS Free Full-Text TNMplot.com: A Web Tool for the ... - MDPI

Huge whole-genome study of human metastatic cancers - Nature

WebCancer mortality data for 2024 are available and can be accessed at CDC’s National Center for Health Statistics (NCHS) National Vital Statistics System (NVSS). The tool also presents survival and prevalence estimates, which are based on CDC’s National Program of Cancer Registries (NPCR) data covering 88% of the U.S. population. WebIndividual patient data analysis of progression-free survival versus overall survival as a first-line end point for metastatic colorectal cancer in modern randomized trials: findings from the analysis and research in cancers of the digestive system database. 2015. Shi, Qian; de Gramont, Aimery; hbf 255t hbf 256t違いWeb25 Nov 2024 · MetaTropismDB: a database of organ-specific metastasis induced by human cancer cell lines in mouse models MetaTropismDB: a database of organ … gold and or silver locket

"WebStudies based on the TCGA database led us to investigate the potential role of GPX2 in cervical cancer cell lines. First, we used qRT-PCR and Western blot analysis to examine GPX2 expression in ME180 and HeLa cells. ... Notes: (A) Pictures of H&E and GPX2 IHC in human cervical cancer tissues and metastatic lymph nodes (20X and 40X microscopes ... " - Human metastatic cancer database

Human metastatic cancer database

CXCL14 promotes metastasis of non-small cell lung cancer

Web27 Feb 2024 · The metastasis of lung cancer cells was evaluated in an orthotopic model. Results: We have presented that overexpression of CXCL14 and ACKR2 was observed in lung cancer datasets, human lung tumor sections, and lung cancer cells. Furthermore, the migration of CXCL14-promoted lung cancer cells was determined in vitro and in vivo. In … Web14 Apr 2024 · HR-positive breast cancer with at least one endocrine therapy and disease progression was judged by the investigator to no longer benefit from endocrine therapy. Has been treated with 0 to 1 prior lines of chemotherapy in the metastatic setting. Has documented radiologic progression (during or after most recent treatment).

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WebIntroduction. Approximately 20% of colorectal cancer (CRC) cases are found to have distant metastasis at the time of diagnosis, and the 5-year survival rate is <8%. 1 The most common metastasis sites of CRC are the liver, lung, and peritoneum, but other metastatic sites have been described, such as bone, spleen, brain, and distant lymph nodes. 2–4 A …

Web12 Apr 2024 · Abstract. Intratumour heterogeneity (ITH) fuels lung cancer evolution, which leads to immune evasion and resistance to therapy 1. Here, using paired whole-exome and RNA sequencing data, we ... WebHere, we presented a database, HCMDB (the human cancer metastasis database, http://hcmdb.i-sanger.com/index), which is freely ac- cessible to the research community …

Web1 Jan 2024 · Europe PMC is an archive of life sciences journal literature. Search life-sciences literature (42,004,711 articles, preprints and more) (42,004,711 articles, … Web12 Apr 2024 · Furthermore, the metastases could be associated with either one clone (monoclonal) or more than one clone (polyclonal). Read the paper: …

WebThis section of the Human Protein Atlas focuses on the expression profiles in human tissues of genes both on the mRNA and protein level. The protein expression data from 44 normal human tissue types is derived from antibody-based protein profiling using conventional and multiplex immunohistochemistry.

Web4 Jan 2024 · HCMDB: the human cancer metastasis database. Metastasis is the main event leading to death in cancer patients. Over the past decade, high-throughput … gold and pawn kingstonWeb12 Apr 2024 · Previous studies have indicated that the adrenergic receptor signaling pathway plays a fundamental role in chronic stress-induced cancer metastasis. In this study, we investigated whether an ethanol extract of Perilla frutescens leaves (EPF) traditionally used to treat stress-related symptoms by moving Qi could regulate the … hbf-255 hbf-256 違いWeb11 Jul 2024 · The GENT2 database provides the following five functions: 1) a landscape of gene expression profile across 72 normal and tumor tissues, 2) cancer subtype profiling, 3) statistical significance of gene expression difference between normal and tumor samples, 4) a prognostic value of gene expression, and 5) meta-survival analysis (Fig. 1). The … gold and passionWeb1 Jan 2024 · HCMDB is freely accessible to cancer metastasis research community to query and analyze metastasis-related expression data. We expected this database could facilitate the identification of cancer metastasis associated genes and benefit the examination of their roles in physiological and pathological processes of cancer metastasis. hbf255t-wWeb24 Feb 2024 · PDX models representing the deadliest forms of breast cancer. We previously reported that breast PDXs recapitulated key tumor characteristics, including metastasis and clinical outcomes 13.We now ... hbf256twWeb17 Dec 2024 · GLOBOCAN 2024 is an online database providing global cancer statistics and estimates of incidence and mortality in 185 countries for 36 types of cancer, and for all cancer sites combined. The data is part of IARC’s Global Cancer Observatory, and is available online at Cancer Today with user-friendly facilities to produce maps and … hbf256tWeb3 Feb 2024 · In our study, we have gone through the manual process of extracting and mapping to reference ontologies detailed clinical features (9 items) associated to each patient cohort and datasets. In comparison with the other resources, IMMUcan scDB is the only database specifically dedicated to human cancer single-cell transcriptomic … hbf255t 価格