WebA two-generation reproductive toxicity study in rats exposed to dichloromethane b y inhalation at concentrations of up to 5300 mg/m3, 6 h/day, 5 days/week, did not show evidence of an adverse effect on any reproductive parameter, neonatal survival or neonatal growth in either the F0 or F1 generation. WebExperiment 1 (dichloromethane tested individually): 3 Experiment 2 (dichloromethane examined simultaneously with three other solvents on separate skin areas): 3 Details on study design: TEST SITE - Area of exposure: 1 inch x 1 inch - Type of wrap if used: patches fixed to the application sites by means of adhesive tape and the entire trunk of ...
Registration Dossier - ECHA - Europa
WebNov 10, 2024 · Methylene chloride, also known as dichloromethane and DCM, is a volatile chemical used in a wide range of industrial, commercial, and consumer applications. Information from the 2016 Chemical Data Reporting (CDR) for methylene chloride indicates the reported production volume is more than 260 million pounds per year (domestic … Webdichloromethane; methylene chloride EC number: 200-838-9 CAS number: 75-09-2 Genetic toxicity: in vitro Currently viewing: Administrative data Data source Materials and methods Results and discussion Applicant's summary and conclusion Administrative data Endpoint: in vitro gene mutation study in bacteria Type of information: experimental study new mexico nuclear museum
Evaluation of the carcinogenicity of dichloromethane in rats, …
WebL'ECHA vient de publier sa proposition d'actualisation du Plan d'action continu communautaire (Community rolling action plan - CoRAP). Dichloromethane (DCM or methylene chloride, methylene bichloride) is an organochlorine compound with the formula CH2Cl2. This colorless, volatile liquid with a chloroform-like, sweet odour is widely used as a solvent. Although it is not miscible with water, it is slightly polar, and miscible with many organic solvents. WebMar 1, 2024 · 1. Introduction. Dichloromethane (DCM; Methylene Chloride; CH 2 Cl 2; CAS no. 75-09-2), a liquid with a high vapor pressure, belongs to the family of chlorinated methanes, e.g., carbon tetrachloride, chloroform, and methyl chloride, for which there is an extensive toxicology database demonstrating similarities and differences.They all can be … new mexico nurse practice act