Cytoskeleton-associated protein 4
CKAP4 as a receptor of APF plays an important role in mediating bladder carcinoma cells proliferation. Following CKAP4 knockdown, the inhibition effect of APF on T24 cell proliferation was eliminated, indicating the important role of the receptor in mediating the antiproliferation activity of APF in bladder cancer … See more Our group investigated the relationship between CKAP4/DHHC2 expression and prognosis in 416 patients with hepatocellular carcinoma (HCC) (Li et al., 2014b) (Table 2). … See more Previous studies reported that CKAP4 as an ER enriched protein could be secreted by exosomes of ovarian and colon cancer cells and detected as an exosomal protein in urine (Gonzales et al., 2009; Demory Beckler et al., 2013; … See more Although plentiful researches focused on the relationship between CKAP4 and cancer, there were also studies that showed that CKAP4 played an important role in noncancers. … See more Sufficient studies have confirmed that CKAP4 correlated with various cancers’ progress and prognosis. The formation of the xenograft tumors derived from CKAP4-depleted cells, including lung cancer cells (Kimura et al., 2016), … See more WebJan 8, 2024 · Suggest a role for cytoskeleton-associated protein 4 in modulating fibroblast activation in the injured heart. CLIMP-63 (also known as CKAP4), is the partner of triadin, is responsible for this association of triads and microtubules. p63 positively regulates desmosome adhesion by directly controlling the expression of several desmosome genes ...
Cytoskeleton-associated protein 4
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WebIn cell biology, microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs are integral to the stability of the cell and its internal structures and the transport of components within the cell. ... "XMAP215: a key component of the dynamic microtubule cytoskeleton". Trends Cell ... WebFeb 22, 2014 · Cytoskeleton-associated membrane protein 4 (CKAP4), also known as P63, with a molecular weight 63 kilodaltons, is a type of type II transmembrane protein that is located in the endoplasmic reticulum. 3, …
WebActivity-regulated cytoskeleton-associated protein is a plasticity protein that in humans is encoded by the ARC gene. It was first characterized in 1995. [5] [6] ARC is a member of … WebActivity-regulated cytoskeleton-associated protein is a plasticity protein that in humans is encoded by the ARC gene. It was first characterized in 1995. [5] [6] ARC is a member of the immediate-early gene (IEG) family, a rapidly activated class of genes functionally defined by their ability to be transcribed in the presence of protein ...
WebAppropriate cytoskeletal organization is essential for vascular smooth muscle cell (VSMC) conditions such as hypertension. This study identifies FXR1 … WebWhat Is the Cytoskeleton Made Of? The cytoskeleton of eukaryotic cells is made of filamentous proteins, and it provides mechanical support to the cell and its cytoplasmic constituents. All...
WebMar 21, 2024 · Cytoskeleton-associated protein 4 (CKAP4) is a non-glycosylated type II transmembrane protein that serves as a cell surface-activated receptor. It is expressed primarily in the plasma membranes of bladder epithelial cells, type II alveolar pneumocytes, and vascular smooth muscle cells.
WebApr 12, 2024 · It is worth mentioning that HSP90 135, OSTF1 136, VDAC2 137, RPs 138,139, mitochondrial genes 140, Col2A1 141, and cytoskeleton-associated proteins 142,143,144, are all targets for MYC. poverty cooking recipesWebFeb 22, 2014 · Cytoskeleton-associated membrane protein 4 (CKAP4), also known as P63, with a molecular weight 63 kilodaltons, is a type of type II transmembrane protein … poverty contributionWebSep 4, 2009 · Palladin is an actin cytoskeleton–associated protein which is crucial for cell morphogenesis and motility. Previous studies have shown that palladin is localized to the … poverty country in the world 2021WebJun 1, 2024 · CKAP4 is a 63-kDa non-glycosylated and reversibly palmitoylated type II transmembrane protein that has been shown to anchor rough endoplasmic reticulum … poverty cornerWebJul 8, 2024 · Synaptic activity mediates information storage and memory consolidation in the brain and requires a fast de novo synthesis of mRNAs in the nucleus and proteins in synapses. Intracellular localization of a protein can be achieved by mRNA trafficking and localized translation. Activity-regulated cytoskeleton-associated protein (Arc) is a … toussaint brian w mdWebSt. Paul et al. show that FXR1 links mRNA processing with actin dynamics in vascular smooth muscle cells by binding to mRNAs and proteins that regulate the cytoskeleton. Deletion of FXR1 leads to decreased cellular migration, adhesion, and contraction. Additionally, mice without FXR1 have decreased blood pressure. poverty controlWebThat said, the prokaryotic cytoskeleton is not made of tubulin or actin, but of proteins that resembles these eukaryotic proteins. I refer you to the primary review article: "The … poverty cornwall uk